Evaluation of the anti-stress effects of five Tunisian aromatic and medicinal plants in vitro

The present study was designed to evaluate the anti-stress effects of ethanol extracts five medicinal plants from Southern part Tunisia, traditionally used in folk medicine: Cymbopogon schoenanthus Spreng. (CSEE), Crithmum maritimum L. (CMEE), Arthrophytum scoparium (Pomel) ll’jin (ASEE), Artemisia herba-alba Asso. (AHEE), and Rhanterium suaveolens Desf. (RSEE). Assays using SH-SY5Y cells HSP47-transformed CHO (HSP47+/− cells) were performed. Heat (at 42 °C, for 90 min) induce stress pre-treated cells. tested at 1/1000 dilution significantly enhanced reversal heat shock protein expression heat-stressed HSP47+/- as shown by proteins HSP27, HSP70 HSP90 mRNAs heat-treated Moreover, CSEE 1/100 (v/v) dilutions showed no cytotoxic on both HSP47-/+ In addition, results demonstrated that RSEE promoted recovery acetylcholine (Ach) compared These suggest C. schoenanthus, maritimum, R. can modulate stress, a follow up bioactivities these species may offer new source phytomedicines effective treatment stress-related diseases.